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Research Project by Gifted Gabber Alumni - Sebastian Leung
Project's Result
Published in the Journal of Student Research: Access the Full Paper Here
Gifted Gabber Research Program
This impactful research was conducted during the 2022 Research Program at Gifted Gabber, under the guidance of Research Professor Rajagopal Appavu and Mentor Coach Jo.
Research Summary
Sebastian Leung’s research presents an in-depth exploration of the molecular inhibition of phagocytosis, a critical process in the body’s immune response. Phagocytosis, the mechanism by which immune cells engulf and neutralize harmful pathogens, is a cornerstone of human immunity. However, certain molecular interactions can inhibit this process, leading to compromised immune defense.
This systematic review investigates the biological pathways and molecular factors that impede phagocytosis, shedding light on their implications for immune-related disorders and infections. Sebastian’s research highlights how these inhibitors operate, the diseases they exacerbate, and potential therapeutic strategies to counteract their effects.
Key findings emphasize the importance of targeting specific molecular interactions to restore or enhance phagocytic activity, offering promising avenues for immunotherapy and precision medicine. The study underscores the delicate balance of immune regulation and the necessity for continued research into molecular interventions.
Sebastian’s work stands as a vital contribution to the understanding of immune system dynamics, providing a foundation for developing innovative treatments for immune-compromising conditions.